Publikationen von Sarah E. O’Connor

Bradley, S. A.; Lehka, B. J.; Hansson, F. G.; Adhikari, K. B.; Rago, D.; Rubaszka, P.; Haidar, A. K.; Chen, L.; Hansen, L. G.; Gudich, O. et al.; Giannakou, K.; Lengger, B.; Gill, R. T.; Nakamura, Y.; de Bernonville, T. D.; Koudounas, K.; Romero-Suarez, D.; Ding, L.; Qiao, Y.; Frimurer, T. M.; Petersen, A. A.; Besseau, S.; Kumar, S.; Gautron, N.; Melin, C.; Marc, J.; Jeanneau, R.; O’Connor, S. E.; Courdavault, V.; Keasling, J. D.; Zhang, J.; Jensen, M. K.: Biosynthesis of natural and halogenated plant monoterpene indole alkaloids in yeast. Nature Chemical Biology 19, S. 1551 - 1560 (2023)

Florean, M.; Luck, K.; Hong, B.; Nakamura, Y.; O’Connor, S. E.; Köllner, T. G.: Reinventing metabolic pathways: Independent evolution of benzoxazinoids in flowering plants. Proceedings of the National Academy of Sciences of the United States of America 120 (42), e2307981120 (2023)

Grzech, D.; Hong, B.; Caputi, L.; Sonawane, P. D.; O’Connor, S. E.: Engineering the biosynthesis of late-stage vinblastine precursors precondylocarpine acetate, catharanthine, tabersonine in Nicotiana benthamiana. ACS Synthetic Biology 12 (1), S. 27 - 34 (2023)

Kunert, M.; Langley, C.; Lucier, R.; Ploß, K.; Rodriguez Lopez, C. E.; Serna Guerrero, D. A.; Rothe, E.; O’Connor, S. E.; Sonawane, P. D.: Promiscuous CYP87A enzyme activity initiates cardenolide biosynthesis in plants. Nature Plants 9, S. 1607 - 1617 (2023)

Laforest, L. C.; Kuntz, M. A.; Kanumuri, S. R. R.; Mukhopadhyay, S.; Sharma, A.; O’Connor, S. E.; McCurdy, C. R.; Nadakuduti, S. S.: Metabolite and molecular characterization of Mitragyna speciosa identifies developmental and genotypic effects on monoterpene indole and oxindole alkaloid composition. Journal of Natural Products 86 (4), S. 1042 - 1052 (2023)

Lawas, L. M. F.; Kamileen, M. O.; Buell, C. R.; O’Connor, S. E.; Leisner, C. P.: Transcriptome-based identification and functional characterization of iridoid synthase involved in monotropein biosynthesis in blueberry. Plant Direct 7 (7), e512 (2023)

Li, C.; Wood, J. C.; Vu, H. A.; Hamilton, J. P.; Lopez, C. E. R.; Payne, R. M. E.; Serna Guerrero, D. A.; Gase, K.; Yamamoto, K.; Vaillancourt, B. et al.; Caputi, L.; O’Connor, S. E.; Buell, C. R.: Single-cell multi-omics in the medicinal plant Catharanthus roseus. Nature Chemical Biology 19 (8), S. 1031 - 1041 (2023)

Lorensen, M. D. B. B.; Bjarnholt, N.; St-Pierre, B.; Heinicke, S.; Courdavault, V.; O’Connor, S. E.; Janfelt, C.: Spatial localization of monoterpenoid indole alkaloids in Rauvolfia tetraphylla by high resolution mass spectrometry imaging. Phytochemistry 209, 113620 (2023)

Schäfer, E.; Seibold, P. S.; Bartram, S.; Trottmann, F.; Haensch, V. G.; Gressler, M.; Chadeayne, A. R.; Hertweck, C.; O’Connor, S. E.; Hoffmeister, D.: A „magic mushroom“ multi-product sesquiterpene synthase. ChemBioChem: A European Journal of Chemical Biology 24 (21), e202300511 (2023)

Schotte, C.; Jiang, Y.; Grzech, D.; Dang, T.-T. T.; Laforest, L. C.; León, F.; Mottinelli, M.; Nadakuduti, S. S.; McCurdy, C. R.; O’Connor, S. E.: Directed biosynthesis of mitragynine stereoisomers. Journal of the American Chemical Society 145 (9), S. 4957 - 4963 (2023)

Sonawane, P. D.; Gharat, S. A.; Jozwiak, A.; Barbole, R.; Heinicke, S.; Almekias-Siegl, E.; Meir, S.; Rogachev, I.; O’Connor, S. E.; Giri, A. P. et al.; Aharoni, A.: A BAHD-type acyltransferase concludes the biosynthetic pathway of non-bitter glycoalkaloids in ripe tomato fruit. Nature Communications 14, 4540 (2023)

Stander, E. A.; Lehka, B.; Carqueijeiro, I.; Cuello, C.; Hansson, F. G.; Jansen, H. J.; De Bernonville, T. D.; Williams, C. B.; Vergès, V.; Lezin, E. et al.; Lorensen, M. D. B. B.; Dang, T.-T.; Oudin, A.; Lanoue, A.; Durand, M.; Giglioli-Guivarch, N.; Janfelt, C.; Papon, N.; Dirks, R. P.; O’Connor, S. E.; Jensen, M. K.; Besseau, S.; Courdavault, V.: The Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids. Communications Biology 6, 1197 (2023)

Stephan, P.; Langley, C.; Winkler, D.; Basquin, D. J.; Caputi, L.; O’Connor, S. E.; Kries, D. H.: Gerichtete Evolution von Piperazinsäureeinbau durch eine Nichtribosomale Peptidsynthetase. Angewandte Chemie 135 (35), e202304843 (2023)

Stephan, P.; Langley, C.; Winkler, D.; Basquin, J.; Caputi, L.; O’Connor, S. E.; Kries, H.: Directed evolution of piperazic acid incorporation by a nonribosomal peptide synthetase. Angewandte Chemie International Edition 62 (35), e202304843 (2023)

Boccia, M.; Grzech, D.; Lopes, A. A.; O’Connor, S. E.; Caputi, L.: Directed biosynthesis of new to nature alkaloids in a heterologous Nicotiana benthamiana expression host. Frontiers in Plant Science 13, 919443 (2022)

Cuello, C.; Stander, E. A.; Jansen, H. J.; De Bernonville, T. D.; Oudin, A.; Williams, C. B.; Lanoue, A.; Guivarc'h, N. G.; Papon, N.; Dirks, R. P. et al.; Jensen, M. K.; O’Connor, S. E.; Besseau, S.; Courdavault, V.: An updated version of the Madagascar periwinkle genome. F1000Research 11, 1541 (2022)

Cuello, C.; Stander, E. A.; Jansen, H. J.; Dugé De Bernonville, T.; Lanoue, A.; Giglioli-Guivarch, N.; Papon, N.; Dirks, R. P.; Jensen, M. K.; O’Connor, S. E. et al.; Bessau, S.; Courdavault, V.: Genome assembly of the medicinal plant Voacanga thouarsii. Genome Biology and Evolution 14 (11), evac158 (2022)

DeMars, M.; Nakamura, Y.; Kamileen, M. O.; Sanders, J. N.; Paetz, C.; Houk, K. N.; O’Connor, S. E.: Mechanism and evolution of [4+2] cyclases in monoterpene indole alkaloid biosynthesis. Faseb Journal 36 (S1) (2022)

Dudley, Q. M.; Jo, S.; Serna Guerrero, D. A.; Chhetry, M.; Smedley, M. A.; Harwood, W. A.; Sherden, N. H.; O’Connor, S. E.; Caputi, L.; Patron, N. J.: Reconstitution of monoterpene indole alkaloid biosynthesis in genome engineered Nicotiana benthamiana. Communications Biology 5, 949 (2022)

Hernández-Lozada, N. J.; Hong, B.; Wood, J. C.; Caputi, L.; Basquin, J.; Chuang, L.; Kunert, M.; Rodriguez Lopez, C. E.; Langley, C.; Zhao, D. et al.; Buell, C. R.; Lichman, B. R.; O’Connor, S. E.: Biocatalytic routes to stereo-divergent iridoids. Nature Communications 13, 4718 (2022)