Publications of Sarah E. O'Connor

DellaPenna, D.; O'Connor, S. E.: Plant gene clusters and opiates. Science 336 (6089), pp. 1648 - 1649 (2012)

Geu-Flores, F.; Sherden, N. H.; Courdavault, V.; Burlat, V.; Glenn, W. S.; Wu, C.; Nims, E.; Cui, Y.; O'Connor, S. E.: An alternative route to cyclic terpenes by reductive cyclization in iridoid biosynthesis. Nature 492 (7427), pp. 138 - 142 (2012)

Gongora-Castillo, E.; Childs, K. L.; Fedewa, G.; Hamilton, J. P.; Liscombe, D. K.; Magallanes-Lundback, M.; Mandadi, K. K.; Nims, E.; Runguphan, W.; Vaillancourt, B. et al.; Varbanova-Herde, M.; DellaPenna, D.; McKnight, T. D.; O'Connor, S. E.; Buell, C. R.: Development of transcriptomic resources for interrogating the biosynthesis of monoterpene indole alkaloids in medicinal plant species. PLoS One 7 (12), e52506 (2012)

Panjikar, S.; Stoeckigt, J.; O'Connor, S. E.; Warzecha, H.: The impact of structural biology on alkaloid biosynthesis research. Natural Product Reports 29 (10), pp. 1176 - 1200 (2012)

Ruff, B. M.; Braese, S.; O'Connor, S. E.: Biocatalytic production of tetrahydroisoquinolines. Tetrahedron Letters 53 (9), pp. 1071 - 1074 (2012)

Runguphan, W.; Glenn, W. S.; O'Connor, S. E.: Redesign of a dioxygenase in morphine biosynthesis. Chemistry & Biology 19 (6), pp. 674 - 678 (2012)

Giddings, L.-A.; Liscombe, D. K.; Hamilton, J. P.; Childs, K. L.; DellaPenna, D.; Buell, C. R.; O'Connor, S. E.: A stereoselective hydroxylation step of alkaloid biosynthesis by a unique cytochrome P450 in Catharanthus roseus. The Journal of Biological Chemistry 286 (19), pp. 16751 - 16757 (2011)

Glenn, W. S.; Nims, E.; O'Connor, S. E.: Reengineering a tryptophan halogenase to preferentially chlorinate a direct alkaloid precursor. Journal of the American Chemical Society 133 (48), pp. 19346 - 19349 (2011)

Goetz, K. E.; Coyle, C. M.; Cheng, J. Z.; O'Connor, S. E.; Panaccione, D. G.: Ergot cluster-encoded catalase is required for synthesis of chanoclavine-I in Aspergillus fumigatus. Current Genetics 57 (3), pp. 201 - 211 (2011)

Hicks, M. A.; Barber II, A. E.; Giddings, L.-A.; Caldwell, J.; O'Connor, S. E.; Babbitt, P. C.: The evolution of function in strictosidine synthase-like proteins. Proteins: Structure, Function, and Bioinformatics 79 (11), pp. 3082 - 3098 (2011)

Liscombe, D. K.; O'Connor, S. E.: A virus-induced gene silencing approach to understanding alkaloid metabolism in Catharanthus roseus. Phytochemistry 72 (16), pp. 1969 - 1977 (2011)

Bernhardt, P.; Usera, A. R.; O'Connor, S. E.: Biocatalytic asymmetric formation of tetrahydro-beta-carbolines. Tetrahedron Letters 51 (33), pp. 4400 - 4402 (2010)

Cheng, J. Z.; Coyle, C. M.; Panaccione, D. G.; O'Connor, S. E.: Controlling a structural branch point in ergot alkaloid biosynthesis. Journal of the American Chemical Society 132 (37), pp. 12835 - 12837 (2010)

Cheng, J. Z.; Coyle, C. M.; Panaccione, D. G.; O'Connor, S. E.: A role for old yellow enzyme in ergot alkaloid biosynthesis. The Journal of Physical Chemistry B 132 (6), pp. 1776 - 1777 (2010)

Coyle, C. M.; Cheng, J. Z.; O'Connor, S. E.; Panaccione, D. G.: An old yellow enzyme gene controls the branch point between Aspergillus fumigatus and Claviceps purpurea ergot alkaloid pathways. Applied and Environmental Microbiology 76 (12), pp. 3898 - 3903 (2010)

Liscombe, D. K.; Usera, A. R.; O'Connor, S. E.: Homolog of tocopherol C methyltransferases catalyzes N methylation in anticancer alkaloid biosynthesis. Proceedings of the National Academy of Sciences of the United States of America 107 (44), pp. 18793 - 18798 (2010)

Runguphan, W.; Qu, X.; O'Connor, S. E.: Integrating carbon-halogen bond formation into medicinal plant metabolism. Nature 468, pp. 461 - 464 (2010)

Bernhardt, P.; O'Connor, S. E.: Synthesis and biochemical evaluation of des-vinyl secologanin aglycones with alternate stereochemistry. Tetrahedron Letters 50 (51), pp. 7118 - 7120 (2009)

Bernhardt, P.; O'Connor, S. E.: Opportunities for enzyme engineering in natural product biosynthesis. Current Opinion in Chemical Biology 13 (1), pp. 35 - 42 (2009)

Bernhardt, P.; Yerkes, N.; O'Connor, S. E.: Bypassing stereoselectivity in the early steps of alkaloid biosynthesis. Organic & Biomolecular Chemistry 7 (20), pp. 4166 - 4168 (2009)